All REAfinity™ Antibody Clones contain the same specifically mutated human IgG1 sequence as their constant region.
This offers the possibility to work with only one type of isotype control, reducing the complexity of experiment planning and saving time.
Hybridoma-derived monoclonal antibodies on the other hand, are composed of antibody isotypes derived from different species and therefore require multiple isotype controls.
This complicates not only the management of reagent inventory, but also panel design when setting up experiments.